Hormonal Signalling Pathways and Molecular Endocrinology

A detailed review of the biochemical mechanisms governing peptide, steroid, and thyroid hormone signalling is provided, with emphasis on receptor-mediated signal transduction cascades and their crosstalk in endocrine physiology. The chapter addresses the molecular basis of hormonal dysregulation in conditions such as type 2 diabetes mellitus, polycystic ovary syndrome, thyroid disorders, and adrenal insufficiency, as well as advances in hormone-targeted therapeutics.