Pharmacology of Inflammation and Analgesics: From COX Inhibition to Cytokine Targeting

An integrated review of anti-inflammatory and analgesic pharmacology is presented, covering classical mechanisms of NSAIDs, glucocorticoids, and opioids alongside the emerging pharmacology of cytokine antagonists, JAK inhibitors, and novel pain pathway modulators. The chapter addresses the therapeutic management of chronic pain and inflammatory disease, with discussion of drug safety profiles and strategies to balance efficacy against adverse effect burdens.