Precision Medicine and Genomics in Prostate Cancer

This chapter examines the application of germline and somatic genomic profiling to the diagnosis, risk stratification, and treatment selection in prostate cancer, with particular focus on BRCA1/2, ATM, and homologous recombination repair gene alterations. It reviews the clinical utility of liquid biopsy, circulating tumor DNA, and polygenic risk scores in contemporary practice. The integration of multi-omics platforms, proteomics, and transcriptomics into precision oncology frameworks for prostate cancer is discussed in detail.