Advances in the Management of Hematological Malignancies: Acute Leukemias, Lymphomas, and Myeloma

The treatment of hematological malignancies has been profoundly reshaped by the introduction of molecularly targeted agents, immunotherapeutic approaches, and cellular therapies. This chapter provides a comprehensive update on recent advances in the management of acute myeloid and lymphoblastic leukemias, diffuse large B-cell and follicular lymphomas, and multiple myeloma, integrating risk stratification frameworks, novel induction and consolidation strategies, transplant considerations, and the emerging role of minimal residual disease assessment in guiding therapeutic decisions.