Cardiorenal Syndrome: Intersecting Pathways, Shared Mechanisms, and Integrated Care

The bidirectional relationship between cardiac and renal dysfunction is reviewed through the framework of cardiorenal syndrome subtypes, with a focus on shared hemodynamic, neurohumoral, and inflammatory mechanisms. This chapter explores evidence-based management strategies for the complex patient with concurrent heart failure and kidney disease, and highlights gaps in current therapeutic approaches that define important research priorities.