Gynecologic Oncology: Emerging Therapies and Precision Medicine Approaches

This chapter provides a comprehensive review of recent developments in the management of gynecologic malignancies — including cervical, endometrial, ovarian, and vulvar cancers — with a focus on the integration of targeted therapies, immunotherapy, and biomarker-driven treatment selection into clinical practice. It reviews the evolving landscape of PARP inhibitors, anti-angiogenic agents, immune checkpoint inhibitors, and antibody-drug conjugates across clinical trial and real-world settings. The chapter also examines advances in sentinel lymph node mapping, fertility-sparing oncologic surgery, and the use of liquid biopsies for disease monitoring and treatment response assessment.