This chapter offers an in-depth analysis of the contemporary management of high-risk pregnancies, encompassing conditions such as preeclampsia, gestational diabetes, preterm labor, and fetal growth restriction. It synthesizes the latest evidence on pathophysiology, biomarker-based prediction, pharmacological interventions, and surveillance strategies that have redefined clinical decision-making in maternal-fetal medicine. The chapter also addresses multidisciplinary care models and the integration of precision medicine into the management of complex obstetric conditions.

Medical Science
High-Risk Pregnancy and Maternal-Fetal Medicine: Current Concepts and Evolving Paradigms
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