Lupus Nephritis and Autoimmune Renal Disorders: Immunopathology and Treatment Advances

Lupus nephritis and related autoimmune nephropathies are reviewed with emphasis on their immunopathological basis, including the role of type I interferon signaling, complement dysregulation, and B-cell hyperactivation. This chapter evaluates established and emerging therapies, including voclosporin, belimumab, and anifrolumab, and discusses the evolving landscape of histopathological classification and precision treatment stratification.