Molecular and Genetic Frontiers in Sensorineural Hearing Loss

This chapter provides an in-depth review of recent advances in the molecular genetics of sensorineural hearing loss, encompassing genome-wide association studies, next-generation sequencing approaches, and the identification of novel pathogenic variants. It critically appraises the translational implications of these discoveries, including gene therapy strategies, inner-ear drug delivery systems, and the emerging prospects for precision medicine in audiological rehabilitation.