Molecular Diagnostics in Hematological Malignancies: Current Landscape and Emerging Technologies

This chapter provides a comprehensive review of the molecular diagnostic tools transforming the detection and classification of hematological cancers, including next-generation sequencing (NGS), digital PCR, and RNA-based assays. It examines the application of these technologies in establishing diagnosis, risk stratification, and measurable residual disease (MRD) monitoring. The chapter also addresses the evolving role of liquid biopsy and cell-free DNA analysis as non-invasive diagnostic modalities in clinical hematology.